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Original: https://doi.org/10.1080/14756366.2025.2606434 Monoamine oxidase B (MAO-B) inhibitors are commonly used to treat Parkinson’s disease, because they help increase dopamine levels in the brain. In this study, researchers designed and made a new group of chemical compounds and tested them to see how well they block the human MAO-B enzyme. Main findings How they work Further … Read more

Original: https://doi.org/10.1080/14756366.2026.2627052 To create environmentally friendly pesticides with new ways of killing insects, researchers designed and made a new group of chemical compounds from scratch. These compounds are called dual-chiral N-cyano sulfilimine-substituted anthranilic diamides. They tested these new chemicals against two harmful insects: Main findings For P. xylostella: How these compounds work The researchers believe … Read more

Original: https://doi.org/10.1080/14786451.2026.2614788 Waste cooking oil (WCO) can be used as a renewable fuel for diesel engines. However, it is thicker (more viscous) than regular diesel, which makes it difficult to use directly in engines. To solve this problem, higher alcohols like n-octanol can be added. Adding n-octanol improves the fuel’s flow and combustion properties, and … Read more

Original: https://jopn.marvdasht.iau.ir/ This paper presents a new design for penternary logic gates based on carbon nanotube field-effect transistors (CNTFETs). CNTFETs are strong candidates to replace MOSFETs because their threshold voltage can be precisely controlled by adjusting the diameter of the nanotubes. Multiple-valued logic (MVL), such as ternary, quaternary, and penternary logic, offers advantages over binary … Read more

Original: https://doi.org/10.5599/admet.2968 Background and purpose: Detecting uric acid (URA) and dopamine (DPA) is challenging because their oxidation signals strongly overlap. Tungsten disulfide nanostructures are promising electrode materials to address this issue due to their low toxicity, low cost, easy fabrication, and high catalytic activity. Experimental approach: We developed an electrochemical sensor by modifying a glassy … Read more

Original: https://doi.org/10.46488/nept.2024.v23i03.051 In recent years, nanotechnology has become widely popular in many fields, such as tissue engineering, drug delivery, biosensors, and environmental pollution control. Carbon-based nanomaterials have attracted special attention because of the unique way their carbon atoms are arranged, which gives them excellent physical, mechanical, and chemical properties. These materials are especially valued because … Read more

Original: https://doi.org/10.1016/j.jhip.2025.12.003 Combining natural biopolymers with two-dimensional (2D) nanomaterials has created new opportunities to develop materials that are high-performance, eco-friendly, and multifunctional. Chitosan is a natural, biodegradable, and biocompatible material that is widely used in medical and environmental fields. However, its applications are limited because it is mechanically weak, does not conduct electricity well, and … Read more

Original: https://doi.org/10.1051/e3sconf/202345808003 Magnetic fluids have special physical properties that make them useful in modern devices such as bearings, seals, and sliding guides. However, their use is limited because they can lose stability and form rigid structures when exposed to strong magnetic fields. One way to improve stability is to reduce the size of the magnetic … Read more

Original: https://doi.org/10.5599/admet.2968 Background and purpose: Detecting uric acid (URA) and dopamine (DPA) is difficult because their signals appear very close to each other. Tungsten disulfide nanostructures are promising electrode materials because they are low-toxic, inexpensive, easy to make, and highly active. Experimental approach: We developed an electrochemical sensor by modifying a glassy carbon electrode with … Read more

Original: https://doi.org/10.1016/j.enceco.2025.12.012 To identify nanomaterials that may pose environmental risks, bioaccumulation testing is required for regulatory assessment. However, applying the OECD fish bioaccumulation Test Guideline (TG) 305 to nanomaterials still requires additional clarification, especially regarding the best exposure method and whether small changes to nanomaterials—such as different surface coatings—affect their potential to accumulate in organisms. … Read more

Original: https://doi.org/10.1016/j.carpta.2025.101062 Natural sulfated polysaccharides (NSPs) are commonly used in food, medicine, and cosmetics. To recreate the properties of these natural materials, chemical sulfation is usually needed. However, traditional sulfation methods often rely on toxic solvents, large amounts of chemicals, and long heating steps. In this study, we report for the first time that cellulose … Read more

Original: https://doi.org/10.1016/j.clema.2025.100363 Without a thorough review of the existing research on carbon-based nanomaterials (CBNs) across different engineering fields, the discipline risks becoming too narrowly focused on specific applications or conditions. This limits our ability to make full use of the multifunctional and cross-disciplinary advantages that CBNs can offer. Carbon-based nanocomposites are a key way to … Read more

Original: https://doi.org/10.1016/j.nxnano.2025.100341 Polyethylene terephthalate (PET) is a common plastic used to make clear bottles for water, sanitizers, and many other liquids. During the COVID-19 pandemic, people used far more PET products, which created a large increase in PET waste. This waste causes environmental problems and makes waste management more difficult. PET contains about 11% fixed … Read more

Original: https://doi.org/10.1038/s42004-021-00609-9 Studying airborne particles while they are still in the air and changing in real time is important for understanding how the atmosphere works. But normally, to take clear images of these tiny particles, scientists need to trap them first. In this study, the authors use a special setup that combines a digital in-line … Read more

Original: https://doi.org/10.1016/j.jdsr.2022.11.001 Biological tissues in our bodies are built in special ways to meet different needs. Hard tissues like teeth and bones are designed to handle force and support our body. Tooth enamel is the hardest and strongest tissue in the human body. Even though it is only a few millimeters thick and cannot repair … Read more

Original: https://doi.org/10.3390/pathogens13060441 Vaccines are very important because they protect us from many diseases. Even though vaccine research has improved a lot, it is still very difficult to create safer and more effective vaccines for serious diseases like Ebola, tuberculosis, and AIDS. Some vaccines we currently use can cause bad reactions in certain people, which makes … Read more

Original: https://doi.org/10.1016/j.csite.2025.106097 This study looks at improving car radiator performance using a hybrid nanofluid made of Al₂O₃ and SiO₂ nanoparticles in a 50:50 water-ethylene glycol mixture. Using detailed computer simulations (CFD) and symbolic regression, the research examined how different air speeds and coolant flow rates affect heat transfer, pressure drop, and friction. The hybrid nanofluid … Read more

Original: https://doi.org/10.1088/2631-7990/ae098e Micro- and nano-devices (MNDs) are very small, precise, and can perform multiple functions, which makes them ideal for applications like microrobots, biomedical devices, and electronic sensors. Making these devices requires extremely precise control over their structure, materials, and functions. Traditional manufacturing methods struggle to build complex 3D structures or integrate multiple materials. Additive … Read more

Original: https://doi.org/10.3390/mi16020114 A simple “compact model” was developed to quickly estimate the performance of tiny electronic devices, like nano-sized piezoelectronic transistors. This model is useful for getting a rough idea of how devices might behave without running complex simulations. The compact model was checked by comparing it with accurate finite element analysis (FEA), which simulates … Read more

Original: https://doi.org/10.1080/16583655.2023.2236368 Replacing some of the atoms in spinel nanoparticles with lanthanum has a big effect on their properties. Using a sol–gel (auto-ignition) method, scientists were able to substitute rare-earth lanthanum ions (La³⁺) into spinel ferrite, making compounds with the formula SrLaxFe₂₋ₓO₄, where x ranged from 0 to 0.10. Adding lanthanum changes the structure, magnetism, … Read more

Original: https://doi.org/10.1002/advs.202504155 Abstract T lymphocytes are pivotal targets in clinical cancer immunotherapy; however, tumor cells frequently evade the T‐cell attacks by altering the intrinsic immunogenicity manifested as adjuvanticity, antigenicity, and reactogenicity. Here, a bacterial outer membrane vesicle (OMVs)‐based nanosystem is presented to elicit robust T‐cell responses by reshaping tumor immunogenicity. OMVs are engineered with vesicular … Read more

Original: https://doi.org/10.1186/s11671-025-04380-x Ovarian cancer is a common and serious cancer of the female reproductive system. Curcumin (Cur) has shown promise as a treatment, but it is difficult to create an effective delivery system that brings curcumin into tumor cells. The development of Zeolitic Imidazolate Frameworks (ZIFs) provides a new platform for delivering anticancer drugs. In … Read more

Original: https://doi.org/10.1016/j.bioactmat.2025.07.042 Resistance to immunotherapy is still a major challenge in treating lung adenocarcinoma (LUAD). To improve treatment outcomes, it is important to find new and effective targets for immunotherapy. By analyzing public databases, we identified ADPRHL1 (also called ARH2) as a gene linked to immune suppression. In this study, we showed that LUAD tumors … Read more

Original: https://doi.org/10.1016/j.mtbio.2025.102496 Neuroblastoma is a difficult childhood cancer to treat because current therapies are limited, often stop working, and can cause serious side effects. In this study, we created a new nanodrug delivery system that targets a protein called CD24 on neuroblastoma cells and delivers two components—cystine and glucose oxidase (GOx)—to trigger a special type … Read more

Original: https://doi.org/10.1016/j.ijpx.2025.100370 Although malaria is now well controlled, it still threatens global health. Artemisinin drugs are the main treatment for malaria, but they do not dissolve well in the body and are removed from the body too quickly, which weakens their effectiveness. To solve these problems and help the drug accumulate more inside the malaria … Read more

Original: https://doi.org/10.1007/s00262-025-04096-y Pancreatic ductal adenocarcinoma (PDAC) is a type of pancreatic cancer that often contains a high number of a specific immune cell called PMN-MDSCs, which suppress T-cell activity and help tumors evade the immune system. These cells use the JAK2/STAT3 pathway to control arginase activity, which inhibits T-cells. Traditional approaches to block PMN-MDSCs systemically … Read more

Original: https://doi.org/10.31083/rcm42781 Coronary artery disease (CAD) is still one of the main causes of illness and death worldwide. The standard treatment is percutaneous coronary intervention (PCI), where a stent is placed in the artery to keep it open. However, long-term problems remain, such as the artery narrowing again (restenosis), blood clots forming in the stent, … Read more

Original: https://doi.org/10.1002/sstr.202500058 Micro- and nanorobots are becoming increasingly important in solving water pollution problems. As water contamination grows worse, new technologies are needed to remove pollutants more efficiently and more selectively than traditional treatment methods. These very small robots can detect, capture, and break down pollutants, offering a major step forward toward more precise and … Read more

Original: https://doi.org/10.1002/advs.202413201 Phosphate and phosphonate drugs play important roles in living organisms. They help regulate biological processes and have many medical uses, such as fighting viruses, bacteria, cancers, and inhibiting certain enzymes. However, their full therapeutic potential has not been realized because current nanoengineering methods are limited. This study introduces a new strategy to create … Read more

Original: https://doi.org/10.1063/5.0239607 Gas vesicles (GVs) are like microscopic, inflatable balloons made inside cells using genetic instructions. They’ve already proven useful as “highlighters” for ultrasound scans (helping doctors see inside the body better), and now scientists are testing them as starters for a powerful ultrasound treatment technique called cavitation—where sound waves make bubbles burst to target … Read more

Original: https://doi.org/10.3390/nano15110830 Imagine drawing super-thin copper wires (as narrow as a fraction of a human hair) directly onto glass using a precise laser—no need for messy chemicals, special masks, vacuum chambers, or carving away extra material. This breakthrough could change how we build the tiniest electronics in the future. Here’s how it works in simple … Read more

original: https://doi.org/10.1371/journal.pone.0312594 Surface plasmon resonance (SPR) is usually used to study how two biomolecules interact. One molecule is attached to a gold surface, and the other flows over it inside a small microfluidic channel. While measuring these interactions, fluid flow and diffusion naturally occur inside the channel, but experiments are normally set up to minimize … Read more

Original: https://doi.org/10.1016/j.heliyon.2024.e39611 There is a growing need for better wound dressings that can effectively treat injuries caused by accidents, burns, surgeries, and diabetes. When wounds are serious, it is important to help them heal quickly to avoid long-lasting infections and the formation of biofilms, which are difficult to treat. Nanotechnology has recently played a major … Read more

Original: https://doi.org/10.3390/polysaccharides4040022 Because people are increasingly worried about plastic pollution and fossil-fuel–based materials, natural polymers have become more popular. Among them, polysaccharides from macroalgae and microalgae are attractive because they are natural, abundant, and useful in many fields such as biology, medicine, and food science. These algal polysaccharides can be used to make nanomaterials that … Read more

Original: https://doi.org/10.3389/fbioe.2019.00320 Being able to track therapeutic agents inside the body without surgery is one of the most useful techniques in nanomedicine. Scientists have created many kinds of nanoprobes that can help image tissues and treat diseases such as inflammation, heart disease, and cancer. In this review, we look at the latest progress in developing … Read more

Original: https://doi.org/10.1080/14786451.2017.1333995 Researchers coated two types of tiny inorganic materials – MoS₂ nanotubes and W₁₈O₄₉ nanowires -with two conductive polymers, P3HT and PEDOT. They used a special low-temperature plasma-coating method to do this. The goal was to create new platinum-free counter electrodes for dye-sensitized solar cells (DSSCs), because platinum is expensive. Surface studies confirmed that … Read more

Discovery of novel N-(prop-2-yn-1-yl)-1,2,3,4-tetrahydronaphthalen-1-amine derivatives as MAO-B inhibitors for the treatment of Parkinson’s disease